Penn State vs Clemson Pinstripe Bowl: Prediction, Odds, and How to Watch

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The much-anticipated postseason matchup between Penn State and Clemson in the 2025 Pinstripe Bowl is a far cry from what many had envisioned at the start of the season.

Both teams, once considered top contenders for the College Football Playoff, have seen their seasons derailed by injuries, inconsistency, and missed opportunities.

As they get ready to square off in Yankee Stadium, the spotlight shifts to how each team will handle their depleted rosters.

Motivations—whatever’s left of them—will shape how they show up on game day.

This blog post dives into the storylines, player absences, and strategic quirks that could make this bowl game more interesting than it looks on paper.

Overview of the 2025 Pinstripe Bowl Matchup

The 2025 Pinstripe Bowl features two storied programs: Penn State and Clemson.

Both have experienced unexpectedly challenging seasons.

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Combined, these teams have racked up 11 losses—a sharp contrast to their preseason hype as national championship hopefuls.

Still, the Pinstripe Bowl gives both squads a shot to end their seasons with something, anything, to feel good about.

Coaching Changes and Their Impact

Penn State enters the bowl game in the middle of a coaching transition.

Interim coach Terry Smith is running bowl preparations, while newly hired Matt Campbell is already looking ahead to the long-term picture.

This shift in leadership definitely adds a layer of uncertainty to Penn State’s game plan.

Meanwhile, Clemson’s coaching staff is sticking with what works, at least for now.

Defensive coordinator Tom Allen will be calling the plays from the booth.

Allen, who once spent time at Penn State, brings a little extra insight to the Tigers’ defensive approach.

Key Player Absences

Both teams are missing several key players thanks to injuries, NFL Draft opt-outs, and other reasons.

These absences could really shake up how this game plays out.

Penn State’s Notable Opt-Outs

  • Defensive Tackle: Zane Durant
  • Safety: Zakee Wheatley
  • Running Back: Nicholas Singleton
  • Offensive Lineman: Vega Ioane

These opt-outs leave Penn State with holes in some pretty crucial spots, especially on defense.

The Nittany Lions will have to dig deep and get creative with their depth chart to fill those gaps.

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Clemson’s Depth Challenges

Clemson isn’t exactly at full strength either.

Head coach Dabo Swinney confirmed that 27 scholarship players, including seven starters, won’t suit up for the game.

The Tigers’ roster will be stretched thin, particularly on defense where missing key guys could really sting.

Weather and Playing Conditions

The forecast for the Pinstripe Bowl? Cold—just above freezing.

There’s also a chance of morning ice, which could make the field slick and unpredictable.

These conditions might make things even trickier for both teams, especially if they’re hoping to air it out.

Impact on Game Strategy

With the weather being what it is, both teams might have to lean more on their running games.

Penn State, with Kaytron Allen expected to be available, could have an edge pounding the ball against a depleted Clemson defense.

Historical Context and Motivation

Clemson’s got some history in these kinds of games.

Since 2009, they’ve posted a 5-1 record in non-College Football Playoff or New Year’s Six bowls.

That says something about how Dabo Swinney’s teams tend to handle these matchups.

Motivation as a Decisive Factor

With the big postseason dreams out the window, motivation is going to matter a lot here.

Both teams have something to prove, and you have to wonder who wants it more.

Player Spotlight: Cade Klubnik

Clemson quarterback Cade Klubnik will suit up for his final college game in the Pinstripe Bowl.

He’s put together a strong career—fourth in program history with 73 touchdown passes and 9,930 passing yards.

He’s also just seven completions shy of tying Tajh Boyd for the most career completions in Clemson history.

Klubnik’s Legacy

All eyes will be on Klubnik as he tries to finish his college run on a high note.

Given all the absences, his leadership and experience could be huge for Clemson.

Defensive Play-Calling and Strategy

Penn State safeties coach Anthony Poindexter will handle defensive play-calling for the third time in five seasons.

He’s been here before, so maybe that steadies things a bit for the Nittany Lions’ defense.

Clemson’s Defensive Continuity

Clemson’s sticking with Tom Allen calling plays from the booth.

His experience—and the fact that he knows Penn State pretty well—could give the Tigers a subtle edge.

Predictions and Betting Odds

SportsLine’s computer model ran the matchup 10,000 times, just in case you wondered how close this could be.

The current prediction leans toward Penn State +3.5, so expect a tight, competitive game—at least on paper.

Final Thoughts

Bowl games like the Pinstripe Bowl? They’re tough to predict. There are just so many moving parts.

Coaching changes, player absences, and even the weather—it’s all in the mix. All of that makes this matchup feel wide open and, honestly, a bit wild.

Want more analysis or live updates? Check out CBS Sports.

Joe Hughes
Joe Hughes is the founder of CollegeNetWorth.com, a comprehensive resource on college athletes' earnings potential in the NIL era. Combining his passion for sports with expertise in collegiate athletics, Joe provides valuable insights for athletes, fans, and institutions navigating this new landscape.

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