The 2025 college football season is really starting to sizzle as we head into the all-important Week 10. This weekend could make or break several teams hoping for a spot in the College Football Playoff (CFP) field.
We’re about to dig into some of the biggest games, highlight key players, and toss around a few thoughts on strategy. Whether you live and breathe college football or just tune in when things get interesting, here’s what you might want to watch for in Week 10.
If you want the full scoop, the Fox Sports article that inspired this post is worth a look.
Penn State vs. Ohio State: A Clash of Titans
Penn State and Ohio State meet again, and it’s always a big deal. This year, though, things feel a bit different.
Penn State’s on a rough four-game skid and just swapped coaches mid-season. Meanwhile, Ohio State’s rolling in undefeated and sitting pretty at No. 1 in the AP poll.
What to Expect from Penn State
Penn State’s got nothing left to lose at this point, which could make them dangerous. I wouldn’t be shocked to see them pull out some trick plays and take a few risks on defense.
Even with their recent mess, there’s still talent on this roster. Quarterback Ethan Grunkemeyer, who got the nod against Iowa, now faces an Ohio State defense that’s as tough as they come.
Ohio State’s Dominance
Ohio State just looks unstoppable this season. Their defense, under Matt Patricia, might be the best in college football right now.
They’ve allowed only 41 points all season, which is wild. Guys like Caden Curry, Arvell Reese, Sonny Styles, and Caleb Downs are making life miserable for opposing offenses.
Texas vs. Vanderbilt: A Crucial Homecoming
Texas hasn’t looked like themselves lately, struggling to put away teams they probably should’ve beaten easily. After four straight road games, they’re finally back in Austin to face Vanderbilt.
Texas’ Offensive Struggles
The Longhorns just can’t seem to get the run game going, and a young offensive line isn’t helping. With CJ Baxter maybe back in the mix, there’s hope for a spark.
Quarterback Arch Manning is still in concussion protocol, so Matthew Caldwell might have to step in. That’s not ideal, but sometimes you just have to roll with it.
Vanderbilt’s Challenges
Vanderbilt’s offense sputtered against Missouri, and it doesn’t get any easier against Texas. The Longhorns’ defense is no joke—one of the best in the country, honestly.
Vanderbilt’s going to need something special to keep this one close.
Tennessee vs. Oklahoma: Offensive Firepower vs. Defensive Resilience
This one’s shaping up to be a clash between Tennessee’s explosive offense and Oklahoma’s gritty defense. Tennessee’s offense is ranked No. 2 in the country, led by quarterback Joey Aguilar.
Oklahoma’s Defensive Struggles
Oklahoma’s defense has had its rough patches, especially against Texas and Ole Miss. To make things worse, quarterback John Mateer’s been off his game since injuring his hand.
That’s put a real dent in the Sooners’ ability to put up points.
Home Field Advantage
Tennessee’s got a serious home-field edge, having won 25 straight at home against everyone except Georgia. Maybe that’s just luck, but it could tip the scales in a tight game.
USC vs. Nebraska: A Battle in the Trenches
USC meets Nebraska in a matchup that could nudge the Trojans back into the CFP conversation. USC’s had some bumps lately but seems to be finding their rhythm again.
USC’s Offensive Potential
When USC finds balance, their offense is as dangerous as anyone’s. Nebraska’s run defense has been leaky, which could spell real trouble for them.
If the Trojans stay balanced, they should have the upper hand here.
Nebraska’s Defensive Woes
Nebraska sits near the bottom of the Big Ten in rushing defense—15th, which is rough. They’ll need to step up big time to slow down USC’s attack.
Utah vs. Cincinnati: A Test of Depth
Utah and Cincinnati square off in a game that’ll test both teams’ depth. Utah’s freshman QB Byrd Ficklin turned some heads last week, but this is a different kind of challenge.
Cincinnati’s Offensive Strengths
Brendan Sorsby has quietly been one of the most efficient quarterbacks out there, racking up 26 touchdowns and just one turnover. Still, missing starting running back Evan Pryor could throw a wrench into Cincinnati’s plans.
Utah’s Home Field Advantage
Utah playing at home is a real boost. There’s just something about that energy from the crowd.
Cincinnati’s no pushover, but honestly, Utah’s recent performances have been sharp. With the home fans behind them, it’s hard not to see them as the favorites here.
College football this weekend? It’s shaping up to be wild. If you want a deeper dive or some expert opinions, check out the Fox Sports article.
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